Providing women with containers for DMPA-subcutaneous (DMPA-SC) storage and sharps can help to encourage safe self-injection practices at home. Improper disposal in pit latrines or open spaces remains an implementation challenge to safely scaling this popular and highly effective method. With training from health providers and a provided puncture-proof container, self-injection clients enrolled in a pilot study in Ghana were able to appropriately store and dispose of DMPA-SC injectable contraceptives, offering lessons for scale-up.